Blankedonia Databaseblank mind · numb emotions
Partialpssdnetwork.org

66-nik-doxycycline-anhedonia-fog

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On the 7th day of treatment, I suddenly developed a dramatic change in my body and mind: Complete loss of libido, skin numbness, anhedonia, and intense cognitive fog. It felt like my brain was 'shaken' and disconnected from the world. ... I felt emotionally and sexually dead.
Cause
doxycycline 100mg/day x 10 days (Dec 2020) for an intestinal issue — not an SSRI. Onset day 7; worse after stop. Doctors said psychological; poster rejects that. Later 3-day Wellbutrin trial Sep 2025 intolerable.
Duration
from Dec 2020; emotionally/sexually dead through spring 2021; some small signs summer 2021; persistent at almost 4 years
Recovery notes
Tiny signs (morning erections, some genital sensation) from summer 2021. At ~4 years: anhedonia, low libido, skin numbness, sexual dysfunction remain but less severe than the start. ADJACENT: unique antibiotic cause. Cognitive pole is intense fog / brain 'shaken' and disconnected, not classic empty inner speech.
Source URL
https://www.pssdnetwork.org/patient-spotlight/nik

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